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Foundation for Applied Molecular Evolution


The last half century of medical research has placed chemical structures behind much of biology, including human disease, the human genome, and the origin of life. Scientists at the Foundation have contributed broadly to these activities through innovative and polydisciplinary research in fields as diverse as chemistry, informatics, biology, geology, and astronomy. We are now taking the next steps, to place biological chemistry within its larger "systems" context, from the cell to the organism, and from there to the ecosystem and the planet. Emerging from this are new tools for systems biology and personalized medicine, as well as answers to some "big" questions: Where did we come from? What is our future? Are we alone?

Latest News and Events

April 27, 2013. Research at the FfAME covering artificial genetic systems was described this week by Adam Rutherford in The Guardian of London. They note the "startling progress towards reinventing the language of life", and that for DNA, the "original four-letter alphabet is now up to at least six, with the addition of Z and P by scientists including Steve Benner at the Foundation for Applied Molecular Evolution in Florida."

April 22, 2013. Westheimer Lectureship: In collaboration with Indiana University/Purdue University at Indianapolis (IUPUI) and The Westheimer Institute for Science and Technology (TWIST) in Gainesville, G. Michael Blackburn will be giving three Westheimer Lectures on April 22, April 25, and April 26, entitled:

The Contributions of Frank Westheimer to Biological Organic Chemistry.
Strain Catalysis - Westheimer and Beyond
Resolving Enzyme Mechanisms of Phosphate Transfer

Michael Blackburn is Professor emeritus of Sheffield University, and an expert in enzyme catalysis, phosphorus chemistry, and bioorganic chemistry, all field pioneered by Frank H. Westheimer during his productive lifetime.

February 15, 2013. Steven Benner will be describing the evolutionary history of the interaction between primates and alcohol at the Annual Meeting of the American Society for the Advancement of Science. The presentation is in the Hynes Convention Center in Boston, Friday afternoon, February 15.

December 2, 2012. A podcast at Nature magazine features Steven Benner describing expanded genetic alphabets being developed at the FfAME and at Firebird. It can be found under the title "A new alphabet".

November 21, 2012. The Thiele Foundation has selected General Genomics as one of its BreakoutLabs, GG was founded by Eric A. Gaucher, former President of the FfAME and now at Georgia Tech. Seeking to change how innovative science and technology is funded, the Thiele Foundation funds early stage companies and BreakoutLabs that will, if successful, enable radical advances and have far-reaching impact. General Genomics will use evolutionary analyses to speed the design of medically useful proteins.

November 21, 2012. Roberta Kwok of Nature has published a news feature highlighting work in synthetic biology at the FfAME. Also included is work of a former student and grand-student from the Benner laboratory (respectively, Philip Holliger, now at the MRC in Cambridge. and Ichiro Hirao, now at RIKEN in Yokohoma, Japan).

October 24, 2012. As part of FfAME's outreach activities, Steven Benner will give a lecture on the topic: "What Science is That Religion is Not and Why Scientistis Do So Very Little of It" at 7:00 PM at the Christian Study Center of Gainesville (112 NW 16th St). This is part of the Center's program on "Science and Faith: An Evolving Conversation".

Press Coverage

LiveScience: LiveScience and arsenic-based life
February 1, 2012

Chemical and Engineering News: More on arsenic-based life
January 23, 2012

BBC News: Searching for the origins of life... and our future
November 7, 2011

Odyssey Magazine: The Alien Discovery that Wasn't
June 27, 2011

Chemical & Engineering News: Arsenic Bacterium Debate Continues
June 6, 2011

New Scientist: Arsenic-based bacteria: Fact or fiction?
May 27, 2011

New York Times: A Romp Into Theories of the Cradle of Life
February 21, 2011

Tech News World: Weird Earthly Life-Form Means Rethinking the Hunt for ET
February 21, 2011

MSNBC: Definition of life: Arsenic debate just won't die
February 18, 2011

Yahoo! News: Vatican looks to heavens for signs of alien life
November 10, 2009

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