Postdoctoral Associate

Sankar Basu

Education and work:

• Bachelor of Science (B.Sc), Microbiology (Hons), Chemistry, Mathematics, Bidhannager College, University of Calcutta, India (2005)
• Master of Science (M.Sc.), Biochemistry, University of Calcutta, India (2007)
• Post Msc Associateship course, Biophysical Science, Saha Institute of Nuclear Physics, India (2007-08)
• Ph.D. in Biochemistry (specialization: Computational Biophysics), University of Calcutta, India (2014)

Research Summary:

It is a general notion that structure and function are conserved in orthologs, however for the non-classic type (protein-protein interaction) of action performed by proteins, it has been found to have more and more exceptions. Based on the web-resources already available in the public domain, currently I am trying to analyze chordate gene families and build a database of non-conserved interaction in orthologs which might have implications for personalized medicine in the future. We have initiated with CEACAM (Carcino Embryonic Antigen Cell Adhesion Molecule) as a case study.

Recent Publications

Applications of the Complementarity Plot in error detection and structure validation of proteins
Sankar Basu, Dhananjay Bhattacharyya and Rahul Banerjee
Indian J. Biochem. Biophys. , NISCAIR (2014) 51 (June) (Accepted, In press)

SARAMA: A Standalone Suite of Programs for the Complementarity Plot-A Graphical Structure Validation Tool for Proteins
Sankar Basu, Dhananjay Bhattacharyya and Rahul Banerjee
J. Bioinf. Intell. Control , American Scientific Publishers (2013) 2 (4): 321-323

polDNAmelt: Local Melting Within Polymeric DNA-An Improved Method and Its Applications
Sankar Basu and Dhananjay Bhattacharyya
J. Bioinf. Intell. Control , American Scientific Publishers (2013) 2 (4): 316-320

Self Complementarity within proteins: bridging the gap between binding and folding
Sankar Basu, Dhananjay Bhattacharyya and Rahul Banerjee
Biophys. J. , AP Cell Press (2012) 102 (11): 2605-2614

Mapping the distribution of packing topologies within protein interiors shows predominant preference for specific packing motifs
Sankar Basu, Dhananjay Bhattacharyya and Rahul Banerjee
BMC Bioinformatics (2011) 12:195

(View all publications by Sankar Basu)